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25I-NBF is an N-benzyl derivative of the phenethylamine hallucinogen 2C-I which acts as a highly potent partial agonist for the 5-HT2A receptor.

25I-NBF acts as a partial agonist of human 5-HT2A receptors demonstrating a Ki value of 0.26 nM and an EC50 value of 1.6 nM.

1 A radiolabelled form of 25I-NBF has been used for mapping the distribution of 5-HT2A receptors in the brain, using positron emission tomography.

2 This product is intended for forensic and research applications.

Technical Information
Formal Name
N-(2-fluorobenzyl)-2-(4-iodo-2,5-dimethoxyphenyl)ethanamine, monohydrochloride
CAS Number
Molecular Formula
C17H19FINO2 • HCl
Formula Weight
A crystalline solid
234, 300 nm
InChI Code
InChI Key

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